The Virtual USB Bus Error 39 in Mastercam (versions X7 through 2022) typically occurs when Windows prevents a third-party driver, such as the MultiKey or HASP emulator, from loading due to security restrictions or registry corruption. Below are the standard methods to resolve this error: 1. Disable Core Isolation (Memory Integrity)
If you are reading this, chances are you have just installed Mastercam 2022 (or the X7–2022 generation) on a modern Windows 10 or Windows 11 workstation, only to be greeted by the dreaded Virtual USB Bus Error 39. Your NetHASP or Virtual Key has stopped working, and Mastercam refuses to launch. mastercam+x72022+virtual+usb+bus+error+39+fixed
Step 5: Reinstall Mastercam X7 2022
After the Windows 11 update (or a Windows 10 22H2 cumulative update), Microsoft tightened driver signature enforcement and changed how USBHUB.SYS and Winusb.sys interact with virtual root hubs. The HASP driver—signed with a SHA-1 certificate from 2012—was now considered "untrustworthy." The Virtual USB Bus Error 39 in Mastercam
Memory Integrity (Core Isolation): This is the most frequent culprit on Windows 10 and 11. This security feature prevents unsigned or legacy drivers from loading into high-security memory zones. Your NetHASP or Virtual Key has stopped working,
Error 39 is a Windows operating system error (CM_PROB_DRIVER_FAILED_LOAD). It occurs when: